王廷华

姓名: 王廷华  教授博士生导师

职务: 神经科学研究所所长、实验动物学部主任

电子邮箱:wangtinghua@vip.163.com

研究方向:研究领域涉及临床脑脊髓损伤,脑血管病,老年痴呆,精神疾病,肺损伤,肿瘤(肺癌,结直肠癌,胃癌,胶质瘤),网络药理学, 中医药,干细胞应用,生物信息学,影像组学等多学科交叉

个人简介:

长期致力于临床脑脊髓损伤,脑血管病,老年痴呆,精神疾病,肺损伤,肿瘤(肺癌,结直肠癌,胃癌,胶质瘤),网络药理学, 中医药,干细胞应用,生物信息学,影像组学等多学科交叉的研究,取得多个创新性成果。包括发现肿瘤来源促进神经再生重要分子,提出交叉融合促进学科发展理念。主持国家省部项目20余项,目前以通讯/共同通讯、第一/共同第一作者发表中英文论文500余篇(SCI通讯作者160余篇),其中近5年在Nature CommunicationCell Death Dis等发表SCI论文60余篇,获国家专利8项;主编科学出版社等著作、教材26部(牵头主编国家21世纪生物技术及器官疾病转化图谱教程21部);获中华医学三等奖1项、省部自然科学与科学进步二等奖4项、三等奖5项。目前,担任世界中医药联合会中国综合医院委员会副主任委员,中国研究型医院神经再生与修复委员会常委,中国解剖学会理事,神经解剖专业委员会委员。任四个国家级杂志编委(神经解剖学杂志,中国解剖科学进展等),iDiscoveryiMedicine两本英文杂志主编。获得教育部新世纪优秀人才称号,享受国务院政府特殊津贴,现为教育部长江学者特聘教授评审专家,国家“十四五”规划教材本科临床医学导论及研究生临床研究首席主编。

个人简历:

2012-01-至今,昆明医科大学教授,博导;四川大学特聘教授,博导

2008/05-2011/2,昆明医科大学教授,博导;四川大学特聘教授,博导 2006/05-2018/12,昆明医科大学,神经科学研究所,教授

2003/04-2006/05,昆明医科大学,科研处,教授

2002/07-2003/04,昆明医科大学,神经科学研究所,教授

2000/07-2002/06,法国波尔多第二大学,分子病理学,博士后

1999/09-2000/06,昆明医医科大学,神经科学研究所,副教授,硕导

1989/09-1993/07,昆明医医科大学,人体解剖教研室,助教

1996/09-1999/06, 昆明医科大学,基础医学院学院,人体解剖与组织胚胎学,博士

1993/09-1996/07, 昆明医科大学,基础医学院学院,组织胚胎学与神经生物学,硕士

1984/09-1989/07, 昆明医科大学,临床医学院,临床医学专业,本科

承担科研项目情况:

国家级科研项目

1.      国家自然科学基金面上项目,N0.81471268,针刺促进大鼠损伤脊髓皮质远程调控中SNAP25的作用及7.0T MR分子影像研究,2015.1-2018.1270万,主持

2.      国家自然科学基金面上项目,N0.81271358,针刺促进脊髓可塑性中microRNA124的作用及其对PDXK的调控,2013.1-2016.1270万,主持

3.      国家科技支撑计划子课题,NO.2014BAI01B01,树鼩种质资源培育和人类重大疾病树鼩模型创建及产业化示范,三种神经疾病模型创建及示范研究,2014.1-2016.12,150,主持

省部级科研项目

1.      云南省王文元专家工作站,云南省科技厅,180万元,2022-2025

2.      四川省科技重大项目(社发领域),N0.2020YFS0043MicroRNA-靶基因调控网络在卒中与急性脑损伤中的转化研究,2020.1-2022.3100万,主持

3.      云南省生物医药重大科技专项,N0.2018ZF007-04HPMSCs功能优化干细胞治疗中枢神经系统损伤的安全性和有效性评价,2018.1-2021.12300万,主持

4.      云南省创新团队科技人才和平计划项目,N0.2017HC007,脑损伤转化医学研究省创新团队,2016.10-2019.10200万,主持

5.      云南省自然科学基金重点项目,NO.2014FA009COX5A在脑老化中的作用及其对BDNF信号通路的调控,2014.1-2017.1240万,主持

6.       云南省高校创新团队,高校脑损伤(脑出血)转化医学研究科技创新团队,2014.8.-2016.12120万,主持

代表性论著:

2021

1.      Zhang ZB, Xiong LL, Xue LL, Deng YP, Du RL, Hu Q, Xu Y, Yang SJ, Wang TH. MiR-127-3p targeting CISD1 regulates autophagy in hypoxic-ischemic cortex. Cell Death Dis. 2021 Mar 15;12(3):279.

2.      Jin Huang , Ya-Xin Tan , Lu-Lu Xue , Ruo-Lan Du , Jun-Jie Chen , Li Chen , Ting-Ting Li , Xue Bai , Si-Jin Yang , Liu-Lin Xiong , Ting-Hua Wang. Panax notoginseng saponin attenuates the hypoxic-ischaemic injury in neonatal rats by regulating the expression of neurotrophin factors. Eur J Neurosci , 2021 Sep;54(6):6304-6321.

3.      Rui-Ze Niu , Liu-Lin Xiong , Hao-Li Zhou , Lu-Lu Xue, Qing-Jie Xia, Zheng Ma, Yuan Jin , Li Chen, Ya Jiang, Ting-Hua Wang , Jia Liu. Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway. Chin Med,2021 Oct 18;16(1):105. 

4.      Xue BaiLiu-Lin Xiong,  Chang-Le FangHao-Li Zhou,  Lu-Lu Xue,  Yue Hu,  Qing-Jie Xia,  Jia Liu,  Jun-Yan Zhang,  Ting-Hua Wang and Si-Jin Yang. Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29.Anal Cell Pathol (Amst). 2021; 2021: 6622713.

5.      Hong-Su Zhou,  Ting-Ting Li,  Yu Pi,  Song Wen,  Ting-Hua Wang,  and Liu-Lin Xiong. Ultrasound-Guided Selective Pulsed Radiofrequency Treatment of Great Auricular Nerve for Post-Herpetic Neuralgia of the Head and Neck: A Case Report.J Pain Res. 2021; 14: 3301–3307.

6.      Xiu-Ying HeYang Xu,  Qing-Jie Xia,  Xiao-Ming Zhao,  Shan Li,  Xiao-Qiong HeRu-Rong Wangand Ting-Hua Wang. Combined Scutellarin and C18H17NO6 Imperils the Survival of Glioma: Partly Associated With the Repression of PSEN1/PI3K-AKT Signaling Axis.Front Oncol. 2021; 11: 663262.

7.      Liu-Lin XiongLu-Lu XueYan-Jun ChenRuo-Lan DuQian WangSong WenLin ZhouTao LiuTing-Hua Wang and Chang-Yin Yu. Proteomics Study on the Cerebrospinal Fluid of Patients with Encephalitis. ACS Omega. 2021 Jun 29; 6(25): 16288–16296.

8.      Liu-Lin XiongJie ChenRuo-Lan DuJia LiuYan-Jun ChenMohammed Al HawwasXin-Fu ZhouTing-Hua WangSi-Jin Yang and Xue Bai. Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage. Neural Regen Res. 2021 Aug; 16(8): 1453–1459.

9.      Min-Min LouXiao-Qiang TangGuang-Ming WangJia HeFang Luo,Ming-Feng GuanFei WangHuan ZouJun-Ying WangQun ZhangMing-Jian XuQi-Li ShiLi-Bing ShenGuo-Ming MaYi WuYao-Yang ZhangAi-bin LiangTing-Hua WangLiu-Lin Xiong,Jian WangJun Xuand Wen-Yuan Wang. Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons. Nat Commun. 2021; 12: 4075.

2020

1.       Wang YY, Wang JD, Wang L, Dan QQ, Xia QJ,Wang TH,Xiong LL. Establishment of Neurobehavioral Assessment System in Tree Shrew SCT Model. J Mol Neurosci. 2020 Mar;70(3):308-319.

2.       Xue LL, Wang F,Xiong LL, Du RL, Zhou HL, Zou Y, Wu MX, Yang MA, Dai J, He MX,Wang TH. A single-nucleotide polymorphism induced alternative splicing in Tacr3 involves in hypoxic-ischemic brain damage.Brain Res Bull. 2020 Jan;154:106-115.

3.       Xu Y, Zhao XM, Liu J, Wang YY, Xiong LL, He XY,Wang TH. Complexin I knockout rats exhibit a complex neurobehavioral phenotype including profound ataxia and marked deficits in lifespan.Pflugers Arch. 2020 Jan;472(1):117-133.

4.       Xiong LL, Du RL, Xue LL, Jiang Y, Huang J, Chen L, Liu J,Wang TH. Anti-colorectal cancer effects of scutellarin revealed by genomic and proteomic analysis.Chin Med. 2020 Mar 26;15:28.

5.       Xiao QX, Wen S, Zhang XR, Xue LL, Zhang ZB, Tan YX, Du RL, Zhu ZQ, Zhu YH,Wang TH, Yu CY,Xiong LL. MiR-410-3p overexpression ameliorates neurological deficits in rats with hypoxic-ischemic brain damage. Brain Res Bull. 2020 Sep;162:218-230.

6.       Jiang Y, Bai X, Li TT, Al-Hawwas M, Jin Y, Zou Y, Hu Y, Liu LY, Zhang Y, Liu Q, Yang H, Ma J,Wang TH, Liu J, Xiong LL. COX5A over-expression protects cortical neurons from hypoxic ischemic injury in neonatal rats associated with TPI up-regulation. BMC Neurosci. 2020 Apr 29;21(1):18.

7.       Xiong LL, Xue LL, Al-Hawwas M, Huang J, Niu RZ, Tan YX, Xu Y, Su YY, Liu J,Wang TH. Single-nucleotide polymorphism screening and RNA sequencing of key messenger RNAs associated with neonatal hypoxic-ischemia brain damage.Neural Regen Res. 2020 Jan;15(1):86-95.

8.       Xue LL, Wang F, Niu RZ, Tan YX, Liu J, Jin Y, Ma Z, Zhang ZB, Jiang Y, Chen L, Xia QJ, Chen JJ,Wang TH,Xiong LL. Offspring of rats with cerebral hypoxia-ischemia manifest cognitive dysfunction in learning and memory abilities.Neural Regen Res. 2020 Sep;15(9):1662-1670.               

9.       Xiong LL, Qiu DL, Xiu GH, Al-Hawwas M, Jiang Y, Wang YC, Hu Y, Chen L, Xia QJ,Wang TH. DPYSL2 is a novel regulator for neural stem cell differentiation in rats: revealed by Panax notoginseng saponin administration.Stem Cell Res Ther. 2020 Apr 16;11(1):155.

10.    Ma Z, Wang F, Xue LL, Niu YJ, Hu Y, Su ZY, Huang J, Niu RZ,Wang TH, Ba YC,Xiong LL, Bai X. BbFGF promotes neurological recovery from neonatal hypoxic-ischemic encephalopathy by IL-1β signaling pathway-mediated axon regeneration. Brain Behav. 2020 Aug;10(8):e01696.

11.    Xiong LL, Qin YX, Xiao QX, Jin Y, Al-Hawwas M, Ma Z, Wang YC, Belegu V, Zhou XF, Xue LL, Du RL, Liu J, Bai X,Wang TH. MicroRNA339 Targeting PDXK Improves Motor Dysfunction and Promotes Neurite Growth in the Remote Cortex Subjected to Spinal Cord Transection. Front Cell Dev Biol. 2020 Jul 21;8:577.

12.    Xiao QX, Wen S, Zhang XR, Xue LL, Zhang ZB, Tan YX, Du RL, Zhu ZQ, Zhu YH,Wang TH, Yu CY, Xiong LL. MiR-410-3p overexpression ameliorates neurological deficits in rats with hypoxic-ischemic brain damage.Brain Res Bull. 2020 Sep;162:218-230.

13.    Xiyang YB, Liu R, Wang XY, Li S, Zhao Y, Lu BT, Xiao ZC, Zhang LF,Wang TH, Zhang J.COX5A Plays a Vital Role in Memory Impairment Associated With Brain Agingviathe BDNF/ERK1/2 Signaling Pathway.Front Aging Neurosci. 2020 Jul 10;12:215.

2019

1.       Lin N, Dong XJ, Wang TY, He WJ, Wei J, Wu HY, Wang TH. Characteristics of olfactory ensheathing cells and microarray analysis in Tupaia?belangeri (Wagner, 1841). Mol Med Rep. 2019 Aug;20(2):1819-1825.

2.       Zhao XM, He XY, Liu J, Xu Y, Xu FF, Tan YX, Zhang ZB, Wang TH. Neural Stem Cell Transplantation Improves Locomotor Function in Spinal Cord Transection Rats Associated with Nerve Regeneration and IGF-1 R Expression.Cell Transplant. 2019 Jul 4:963689719860128.

3.       Huang Y, Li SN, Zhou XY, Zhang LX, Chen GX, Wang TH, Xia QJ, Liang N, Zhang X. The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A. Front Neurosci. 2019 Jun 14;13:584.

4.       Xiong LL, Xue LL, Jiang Y, Ma Z, Jin Y, Wang YC, Wang YY, Xia QJ, Zhang Y, Hu Q, Liu J, Wang TH. Suppression of PDGF induces neuronal apoptosis after neonatal cerebral hypoxia and ischemia by inhibiting P-PI3K and P-AKT signaling pathways. Brain Res. 2019 Sep 15;1719:77-88

5.       Wang YY, Niu RZ, Wang JD, Jin Y, Wang TH, Liu F. Establishment of brain ischemia model in tree shrew. Brain Res. 2019 Sep 1;1718:194-200. 

6.       He XY, Xiong LL, Xia QJ, Wang YY, Zhao XM, Du RL, Huang J, He XQ, Jia-Liu, Wang TH. C18H17NO6?and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression. Biomed Res Int. 2019 Feb 20;2019:6821219. doi: 10.1155/2019/6821219. eCollection 2019

7.       He XY, Dan QQ, Wang F, Li YK, Fu SJ, Zhao N, Wang TH. Protein Network Analysis of the Serum and Their Functional Implication in Patients Subjected to Traumatic Brain Injury. Front Neurosci. 2019 Jan 31;12:1049.

8.       Zhang ZB, Tan YX, Zhao Q, Xiong LL, Liu J, Xu FF, Xu Y, Bobrovskaya L, Zhou XF, Wang TH. miRNA-7a-2-3p Inhibits Neuronal Apoptosis in Oxygen-Glucose Deprivation (OGD) Model.Front Neurosci. 2019 Jan 23;13:16. doi: 10.3389/fnins.2019.00016. eCollection 2019.

9.       Zou ZY, Liu J, Chang C, Li JJ, Luo J, Jin Y, Ma Z, Wang TH, Shao JL. Biliverdin administration regulates the microRNA-mRNA expressional network associated with neuroprotection in cerebral ischemia reperfusion injury in rats. Int J Mol Med. 2019 Mar;43(3):1356-1372.

2018

1.       Xu FF, Zhang ZB, Wang YY, Wang TH. Brain-Derived Glia Maturation Factor β Participates in Lung Injury Induced by Acute Cerebral Ischemia by Increasing ROS in Endothelial Cells. Neurosci Bull. 2018 Sep 6. doi: 10.1007/s12264-018-0283-x.

2.       Xiong LL, Zou Y, Shi Y, Zhang P, Zhang RP, Dai XJ, Liu B, Wang TH. Tree shrew neural stem cell transplantation promotes functional recovery of tree shrews with a hemi?sectioned spinal cord injury by upregulating nerve growth factor expression. Int J Mol Med2018 Jun;41(6):3267-3277. doi: 10.3892/ijmm.2018.3553. Epub 2018 Mar 9.

3.       Xiong LL, Hu Y, Zhang P, Zhang Z, Li LH, Gao GD, Zhou XF, Wang TH. Neural Stem Cell Transplantation Promotes Functional Recovery from Traumatic Brain Injury via Brain Derived Neurotrophic Factor-Mediated Neuroplasticity. Mol Neurobiol. 2018 Mar;55(3):2696-2711. doi: 10.1007/s12035-017-0551-1. Epub 2017 Apr 18.

4.       Hu YD, Zhao Q, Zhang XR, Xiong LL, Zhang ZB, Zhang P, Zhang RP, Wang TH. Comparison of the properties of neural stem cells of the hippocampus in the tree shrew and rat in vitro. Mol Med Rep2018 Apr;17(4):5676-5683. doi: 10.3892/mmr.2018.8589. Epub 2018 Feb 12.

5.       Yang J, Xiong LL, Wang YC, He X, Jiang L, Fu SJ, Han XF, Liu J, Wang TH. Oligodendrocyte precursor cell transplantation promotes functional recovery following contusive spinal cord injury in rats and is associated with altered microRNA expression. Mol Med Rep2018 Jan;17(1):771-782. doi: 10.3892/mmr.2017.7957. Epub 2017 Nov 3.

6.       Yang Z, Zhang XR, Zhao Q, Wang SL, Xiong LL, Zhang P, Yuan B, Zhang ZB, Fan SY, Wang TH, Zhang YH. Knockdown of TNF?α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL?10 expression. Int J Mol Med2018 Aug;42(2):926-934. doi: 10.3892/ijmm.2018.3674. Epub 2018May 14.

2017

1.       Hu Y, Xiong LL, Zhang P and Wang TH. Microarray expression profles of genes in lung tissues of rats subjected to focal cerebral ischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation. International Journal of Molecular Medicine, 2017;39: 57-70. 

2.       Xu Y, Wang HW, Luo HY, Shu R, Liu L, Sun L, Han XF, Lin N, Wang TH, Zeng YJ and Wang KH. MicroRNA expression profling of intestinal mucosa tissue predicts multiple crucial regulatory molecules and signaling pathways for gut barrier dysfunction of AIDS patients. Molecular Medicine Reports,2017;16: 8854-8862. 

3.       Lv Q, Zhang ZB, Fu SJ, Xiong LL, Liu J, and Wang TH. Microarray Expression Profile of lncRNAs and mRNAs in Rats with Traumatic Brain Injury after A2B5t Cell Transplantation. Cell Transplantation, 2017; 26(10) 1622-1635 .

4.       Xiong LL, Liu F, Lu BT, Zhao WL, Dong XJ, Liu J, Zhang RP, Zhang P, Wang TH. Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional Improvement Associated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews. Front Cell Neurosci. 2017 Jun 28;11:172. doi: 10.3389/fncel.2017.00172. eCollection 2017. PubMed PMID: 28701922; PubMed Central PMCID: PMC5487382.

5.       Xiong LL, Liu F, Deng SK, Liu J, Dan QQ, Zhang P, Zou Y, Xia QJ, Wang TH. Transplantation of Hematopoietic Stem Cells Promotes Functional Improvement Associated with NT-3-MEK-1 Activation in Spinal Cord-Transected Rats. Front Cell Neurosci. 2017 Jul 19;11:213. doi: 10.3389/fncel.2017.00213. eCollection 2017. PubMed PMID: 28769769; PubMed Central PMCID: PMC5515877.

6.      Han XF, Zhang Y, Xiong LL, Xu Y, Zhang P, Xia QJ, Wang TH, Ba YC. Lentiviral-Mediated Netrin-1 Overexpression Improves Motor and Sensory Functions in SCT Rats Associated with SYP and GAP-43 Expressions.Mol Neurobiol. 2017;54(3):1698. IF 6.19

7.       Pang AL, Xiong LL,  Xia QJ, Liu F, Wang YC, Liu F, Zhang P, Meng BL, Tan S, Wang TH. Neural Stem Cell Transplantation Is Associated with Inhibition of Apoptosis, Bcl-xL Upregulation, and Recovery of Neurological Function in a Rat Model of Traumatic Brain Injury. Cell Transplantation, 2017, 26(7): 1262-1275. IF 3.425  

8.       Zhang ZB, Xiong LL, Lu BT, Zhang HX, Zhang P, Wang TH. Suppression of Trim32 Enhances Motor Function Repair after Traumatic Brain Injury Associated with Antiapoptosis. Cell Transplantation, 2017, 26(7): 1276-1285.  IF 3.425

9.       Li JJ,  Zou ZY, Liu J, Xiong LL, Jiang HY, Wang  TH, Shao JL. Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation. Exp Ther Med. 2017, 14(1):671-679.  IF1.261 

10.   Chen J, Zeng X, Li S, Zhong Z, Hu X, Xiang H, Rao Y, Zhang L,  Zhou X, Xia QJ, Wang TH, Zhang X. Lentivirus-mediated inhibition of AQP4 accelerates motor function recovery associated with NGF in spinal cord contusion rats. Brain Res. 2017, 1669:106-113. IF 2.746 

11.     Jiang L, Xia QJ, Dong XJ, Hu Y, Chen ZW, Chen K, Wang KH, Liu J, Wang TH. Neuroprotective effect of breviscapine on traumatic brain injury in rats associated with the inhibition of GSK3β signaling pathway. Brain Res. 2017;1660:1-9.  IF 2.746 

12.     Jiang L, Hu Y, He X, Lv Q, Wang TH, Xia QJ. Breviscapine reduces neuronal injury caused by traumatic brain injury insult: partly associated with suppression of interleukin-6 expression. Neural Regen Res. 2017;12(1):90-95. IF 1.7 

13.     Hu ZL, Li N, Wei X, Tang L, Wang TH, Chen XM. Neuroprotective effects of BDNF and GDNF in intravitreally transplanted mesenchymal stem cells after optic nerve crush in mice. Int J Ophthalmol. 2017;10(1):35-42. 

14.    Lu  T, Luo  HY, Liu  J, Chen  C, Wang F, Shen  ZW, Liu TL, Zeng YJ, Wang  TH, Wang  KH. Role of Wnt/β-catenin signaling pathway in the repair of intestinal mucosa associated with crypt stem cell in a rat model of abdominal compartment syndrome. Int J Clin Exp Pathol 2017;10(2):2351-2362. 

15.    Yuan B, Xiong LL, Wen MD, Zhang P, Ma HY, Wang THand Zhang YH. Interleukin?6 RNA knockdown ameliorates acute lunginjury induced by intestinal ischemia reperfusion inrats by upregulating interleukin?10 expression . Molecular Medicine Reports, 2017;16: 2529-2537.

16.    Feng GY, Liu J, Wang YC, Wang ZY, Hu Y, Xia QJ, Xu Y, Shang FF, Chen MR, Wang F, Zhou X, Wang TH. Effects of Alpha-Synuclein on Primary Spinal Cord Neurons Associated with Apoptosis and CNTF Expression. Cell Mol Neurobiol,  2017;37:817-829.

17.     Zhong ZQ, Xiang Y, Hu X, Wang YC, Zeng X, Wang XM, Xia QJ, Wang TH, Zhang X. Synaptosomal-associated protein 25 may be an intervention target for improving sensory and locomotor functions afer spinal cord contusion. Neural Regen Res,2017;12(6):969-976.

18.     He X, Jiang L, Dan QQ, Lv Q, Hu Y, Liu J, Wang TH, Wang SF. Bone marrow stromal cells promote neuroplasticity of cerebral ischemic rats via a phosphorylated CRMP2-mediated mechanism.Behav Brain Res. Behav Brain Res. 2017 Mar 1;320:494-503.  IF 3.002 

19.    Liu J, Wang HP, Zou Y, He X, Wang TH. Electro-acupuncture treatment downregulated the CNTF expression in rats with spinal cord transection associated with locomotor function improvement. Experimental and Therapeutic Med Sci Monit. 2017 Sep 2;23:4241-4251.  IF: 1.280.

其他:

科学技术成果奖:

1.      基于“风药开玄”法防治心系疾病的系列研究及应用。科学技术奖二等奖,证书编号:202005-052020.1,第四完成人。

2.      实验树鼩质量标准及七种人类重大疾病动物模型创建关键技术与应用。云南省科学技术进步二等奖,证书编号:2018NC195-R-0032019.5.13,第三完成人。

3.      Notch信号通路介导少突胶质细胞成熟及其在脊髓损伤中的作用与机制。云南省自然科学二等奖,证书编号2017NA113-R-0012018.6.3,第一完成人。

4.      脊髓损伤后细胞因子表达、调控及关键分子作用机制研究。自然科学三等奖,证书编号2016MA237-R-0022017.3.8王廷华排名第二

5.      关键神经营养因子在神经损伤修复中的作用及其分子网络调控,云南省自然科学二等奖,证书编号:2015NA284-R-0012016.6.2,第一完成人。

6.      GFAP转基因干细胞培养移植及抗癫痫大鼠作用的研究。云南省自然科学二等奖,证书编号2009NA421-2-R02,第二完成人。

专著:

1).北京科学出版社《21世纪生物技术》首席主编(12部)

1.       分子杂交理论与技术,科学出版社,200520082013 2015,北京

2.       干细胞理论与技术,科学出版社,2005200820132015,北京

3.       组织细胞化学理论与技术,科学出版社,2005200820132015,北京

4.       PCR理论与技术,科学出版社,2005200820132015,北京

5.       基因克隆理论与技术,科学出版社,2005200820132015,北京

6.       神经细胞培养理论与技术,科学出版社,2005200820132015,北京

7.       蛋白质理论与技术,科学出版社,2005200820132015,北京

8.       抗体理论与技术,科学出版社,2005200820132015,北京

9.       基因沉默理论与技术,科学出版社,2015,北京

10.    生物信息学理论与技术,科学出版社,2015,北京

11.    电生理理论与技术,科学出版社,2015,北京

12.    神经疾病动物模型理论与技术,科学出版社,2015,北京

2) 北京科学出版社《器官比较图谱》首席主编(8部)

1.       心脏比较图谱,北京科学出版社,201810月第一版,王廷华(主编),郜发宝,张云辉,杨思进

2.       肝脏比较图谱,北京科学出版社,201810月第一版,王廷华(主编),胡明道,刘佳

3.       肺脏比较图谱,北京科学出版社,201810月第一版,王廷华(主编),张云辉,王盛兰,李为民

4.       胃肠比较图谱,北京科学出版社,201810月第一版,王廷华(主编),胡建昆,王昆华

5.       脊柱脊髓比较图谱,北京科学出版社,201810月第一版,王廷华(主编),胡侦明,余化霖

6.       脑外伤比较图谱,北京科学出版社,201810月第一版,王廷华(主编),田恒力,赵楠

7.       脑血管病比较图谱,北京科学出版社,201810月第一版,王廷华(主编),闵晓黎,白雪

8.       神经退行性疾病比较图谱,北京科学出版社,201810月第一版,王廷华(主编),商慧芳,白雪,熊柳林

9.       树鼩组织学图谱,云南科技出版社,20177月,王廷华(主编),张荣平,代解杰,刘佳

专利:

1.      王廷华,牛瑞泽,刘佳,鲍天昊。一种实用于树鼩日常运动及繁殖的饲养装置。专利号:ZL201821753232.4,授权公告日:2019.7.2

2.      王廷华,牛瑞泽,刘佳,鲍天昊。一种实用于测试树鼩学习记忆能力的管道迷宫。专利号:ZL201821752995.7,授权公告日:2019.7.2

3.      王廷华,王杰栋,王芳。一种试验用四季树鼩饲养笼具。专利号:ZL201820406211.9,授权公告日:2018.12.25

4.      王廷华,王杰栋,王芳。一种简易的实验用树鼩抓捕网兜。专利号:ZL20172078124.8,授权公告日:2018.3.16

5.      王廷华,王杰栋,刘佳,张荣平。一种用于树鼩跳跃能力检测装置。专利号:ZL201621259281.3,授权公告日:2017.9.5

6.      王廷华,王杰栋,刘佳,张荣平。一种实用于树鼩地面运动能力的装置。专利号:ZL201621405963.0,授权公告日:2017.9.8

7.      王廷华。一种杀灭肿瘤细胞和干细胞的药物及制备方法,中国,201610074060.7

8.      王廷华。一种中枢神经组织细胞高效表达的生长因子重组体的构建方法,中国,201610020807.0

9.      沈勤,王廷华,李小青,李志中,李力燕,欧阳学兵,程彪,何建辉,李静,陈辉,陈雨虹,李劲涛。一种道路交通参与者神经认知行为科学检测方法及装置。CN201410239044.X

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